Immunotherapy is a modern approach to cancer treatment that uses a patient's own immune system to help fight tumors. It has made an incredible impact on treating cancers in many different organ ...

(A) The classic bile acid synthesis pathway: cholesterol 7α-hydroxylase (CYP7A1) converts cholesterol to 7α-hydroxycholesterol (7α-HOC). The sterol 12α-hydroxylase (CYP8B1) converts the intermediate ...

Jaundice coupled with abdominal pain signals a potential bile duct obstruction, a serious condition requiring immediate ...

Immunotherapy is a modern approach to cancer treatment that uses a patient's own immune system to help fight tumors. It has made an incredible impact on treating cancers in many different organ ...

The liver produces bile, which the intestine uses for digestion. For the transport of bile, the liver relies on a network of microscopic tubings, known as bile canaliculi, formed by liver cells called ...

Bile acids, synthesised from cholesterol in the liver, are central to lipid digestion but also serve as signalling molecules that regulate metabolism, inflammation and cellular homeostasis. In ...

The care of patients with cholestatic liver diseases such as primary sclerosing cholangitis (PSC) is challenging, partly due ...

Bile duct cancer, also known as cholangiocarcinoma, is a rare form of cancer that affects the bile ducts. Two bile ducts in the human body connect the liver and gallbladder to the small intestine.

Most of the enzymes involved in drug metabolism are present in the liver. This means the liver plays a key role in drug metabolism. Drug metabolism occurs when the body chemically alters drugs so it ...

Just under a month old, Shaffette had a surgical procedure to connect her liver directly to her small intestine and drain the ...