Engineered T cells that have been used to treat ulcerative colitis, rheumatoid arthritis and lupus show promising results.

A pioneering preclinical study has shown that CAR T cell therapy-a personalized form of immunotherapy used in cancer ...

Today, a new approach is giving patients and their physicians reason to hope. Moffitt Cancer Center has expanded its ...

T-cell therapy represents a groundbreaking advancement in cancer treatment, particularly for hematological malignancies. Despite its potential to offer curative outcomes, the field faces significant ...

Chimeric antigen receptor (CAR) T cell therapy, which uses a patient's own immune cells to fight cancer, has emerged as a powerful way to treat lymphoma and other blood cancers. But researchers have ...

With a five-year survival rate of less than 5%, glioblastoma is one of the most aggressive types of brain cancer.

A new international multicenter study published in the Journal of Cellular and Molecular Medicine provides important real-world evidence on the use of CD19-targeted chimeric antigen receptor (CAR) ...

A phase I study of a next-generation CAR T cell therapy showed a 52 percent complete remission rate for patients with relapsed/refractory lymphoma. A next-generation "armored" CAR T cell therapy ...

Chimeric antigen receptor (CAR) T-cell therapy has shown efficacy in blood cancers — with six CAR T-cell products now approved by the US Food and Drug Administration (FDA) to treat six hematologic ...

The National Institute for Health and Care Excellence (NICE) has approved a chimeric antigen receptor (CAR) T-cell therapy for adults with large B-cell lymphoma. The treatment significantly delays ...

As of September 26, 2024, 33 CD19 CAR T-naïve patients with LBCL (median age, 66 years; median number of previous therapies, 3) received allogeneic CAR T cells. CAR T-cell expansion was observed ...