Figure 1: Algorithm for diagnosis of chronic, progressive ataxia in childhood (excluding infancy), adolescence and adulthood. A full neurological examination to assess gait and standing capacities ...

Type B presents in middle childhood. Types C1 and C2 tend to become ... This is because of ataxia, a neurological condition that causes a lack of control when moving the voluntary muscles.

POLG-related diseases disrupt the function of the mitochondria, or "powerhouses" of the cell — starving them of energy.