Traditionally, we have viewed neurotransmitter release as being strictly confined to presynaptic active zones and postsynaptic densities. New work by Coggan, Bartol and colleagues, using a combination ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 73, No. 11 (Nov., 1976), pp. 4100-4104 (5 pages) Cationic ferritin binds in a time and concentration dependent ...

Figure 1: Ultrastructural localization of nAChRs, GlyRs and gephyrin at discrete postsynaptic membrane microdomains under the calyx-type presynaptic terminal on E15–17 chick ciliary neurons in vivo.

Researchers have constructed a new detailed map of the three-dimensional terrain of a synapse -- the junction between neurons which are critical for communication in the brain and nervous system. The ...

Ciliary Neurotrophic Factor (CNTF) was first characterized as a trophic factor for motor neurons in the ciliary ganglion and spinal cord, leading to its evaluation in humans suffering from motor ...