In addition to regulating the body's fluid balance by excreting greater or smaller amounts of urine, the kidneys also maintain the proper balance of electrolytes (salts) and the pH (an acid-base ...

Congenital urinary tract obstruction is the single most important cause of childhood chronic kidney disease. We have previously demonstrated that human and primate fetal obstruction impairs the ...

aProximate TM is an advanced in vitro model of kidney proximal tubule cells (PTCs) that closely mimics physiological conditions. Derived from fresh human kidney tissue, aProximate TM PTCs are cultured ...

Renal tubular acidosis is a condition where the kidneys are unable to maintain the acid – base balance in the body due to defect in secretion of acid, reabsorption of bicarbonate or both. This results ...