On March 13, 2025, the US Court of Appeals for the Federal Circuit (Federal Circuit) issued a decision titled In Re: Xencor, Inc. (the ...
Researchers from Abl Bio Inc. have published preclinical data for ABL-112, an Fc-competent bispecific antibody (BsAb) targeting TIGIT and 4-1BB (TIGIT x 4-1BB), being developed for the treatment of ...
Pharmaceutical Technology on MSN13d
Lundbeck’s amlenetug gains orphan drug status in Japan for MSALundbeck has gained orphan drug designation (ODD) from Japan’s Ministry of Health, Labor and Welfare (MHLW) for amlenetug to ...
Anti-LAG-3 MAb (Human IgG1) captured on CM5 chip via Anti-Human IgG Fc antibodies surface, can bind Human LAG-3, His Tag (Cat. No. LA3-H5222) with an affinity constant of 4.57 nM as determined in ...
The stem portion confers additional functions to antibodies, including fixing complement and activating immune cells by binding to crystallizable fragment (Fc) receptors. Finally, fragment modes ...
It performs an enzymatic modification method of IgG Fc glycans to perform conjugation. AGLink requires no prior engineering of the amino acid sequence, resulting in stable antibody conjugates ...
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