In vitro ovarian follicle development encompasses the isolation, culture and maturation of ovarian follicles outside the body, with the ultimate aim of generating developmentally competent oocytes.

A recent study published in Nature Communications by researchers at Karolinska Institutet offers new insights into the development of ovarian follicles, which are vital for female fertility as they ...

The mammalian ovary supports reproductive function through the coordinated growth and maturation of oocytes within follicles. Germ cells originate as primordial germ cells that colonise the developing ...

Declining female fertility is a health issue that has received broad global attention. Oocyte quality is the key limiting factor of female fertility, and factors affecting oocyte quality involve the ...

Chronic oral inflammation may impair female fertility by triggering a systemic immune response that affects the ovaries.

Chronic oral inflammation may impair female fertility by triggering a systemic immune response that affects the ovaries. A new study shows this leads to oxidative damage, reduced egg quality, ...

The accumulation of misfolded or damaged proteins in long-lived, non-dividing cells like neurons are linked to neurodegenerative diseases like Alzheimer's. A study now finds that the build-up of these ...

Oestradiol-to-oocyte ratio may predict IVF outcomes in PMOS, with lower ratios linked to better embryo development and clinical results.