Bilateral pallidal deep-brain neurostimulation (DBS) has been shown to improve motor symptoms and overall quality of life in patients with severe primary generalized dystonia, but the long-term ...

June 25, 2008 (Chicago, Illinois) — Twenty-six patients with genetically confirmed DYT1 dystonia had improvement in their motor signs with pallidal deep-brain stimulation (DBS) for at least 3 years ...

February 12, 2008 — Researchers have described a novel, autosomal recessive young-onset dystonia parkinsonism syndrome in 2 Brazilian families, as well as the genetic mutation that appears to underlie ...

The globus pallidus internus (GPi) is the target of choice for the treatment of primary generalized dystonia by deep brain stimulation. Challenging an assumption that large pulse widths (PWs) would be ...

Two patients freed from severe to disabling effects of dystonia through deep brain stimulation therapy continued to have symptom relief for months after their devices accidentally were fully or partly ...

Generalized dystonia usually starts during childhood or the teenage years. It affects groups of muscles in different parts of the body. It usually starts in the trunk or limbs. It often results from ...

Geneva, Switzerland, 4 September 2013 - Addex Therapeutics (ADXN.SW), a leading company pioneering allosteric modulation-based drug discovery and development announced today additional positive ...

A movement-disorder neurologist, Dr. Steven Frucht sees patients with diseases ranging from Parkinson’s and dystonia to tremor and involuntary movement disorders. He counsels 20 to 30 patients with ...

Dystonia is a neurologic movement disorder characterized by involuntary, sustained, patterned, repetitive muscle contractions, usually of opposing muscles. These contractions, which typically affect ...

LOS ANGELES (Feb. 12, 2013) – Two patients freed from severe to disabling effects of dystonia through deep brain stimulation therapy continued to have symptom relief for months after their devices ...