(B) Hypothetical pedigree and molecular analysis showing germ-line mosaicism in tuberous sclerosis. Although this disorder is inherited as an autosomal-dominant trait, the pedigree is more ...

Somatic Mosaicism for SNVs and CNVs In 2014, we found that somatic mosaicism for SNVs and CNVs that also contribute to the germline mosaicism is sig­nificantly more common than previously thought. We ...

The findings “highlight that mosaicism may be more common than we had appreciated so far,” geneticist Anne Goriely of the University of Oxford wrote in an e-mail to The Scientist. “The main value of ...