Figure 1: Ribavirin resistance in patients and cell lines. To determine the clinical relevance of these observations, we examined UGT1A protein levels during response and relapse using confocal ...
Oncotarget published "Altered glucuronidation deregulates androgen dependent response profiles and signifies castration resistance in prostate cancer" which reported that Glucuronidation controls ...
Phase I evaluation of troxacitabine administered by continuous infusion in patients with refractory solid tumors No significant financial relationships to disclose. This is an ASCO Meeting Abstract ...
A number of detoxifying enzymes participate in host defense against endogenous toxins and xenobiotic chemicals. Among these, the UDP-glucuronosyltransferase (UGTs; EC 2.4.1.17) enzymes are found in ...
No significant financial relationships to disclose. This is an ASCO Meeting Abstract from the 2004 ASCO Annual Meeting. This abstract does not include a full text component.
Environmental Health Perspectives, Vol. 105, Supplement 4 (Jun., 1997), pp. 739-747 (9 pages) Glucuronidation and sulfation are phase 2 metabolic reactions catalyzed by large families of different ...
Kanazawa, Japan - One of the main functions of the liver is to detoxify compounds including drugs and toxicants to reduce toxic actions and to eliminate from the human body, requiring a molecular ...
Oncotarget has published "Altered glucuronidation deregulates androgen dependent response profiles and signifies castration resistance in prostate cancer," which reported that glucuronidation controls ...