This podcast comments on a large registry study evaluating the effect of ultra-high-resolution HLA typing on outcomes of unrelated donor transplantation. For patients who are potential candidates for ...
This study did not confirm that UHR 12 out of 12 HLA matching increases the probability of overall survival but does demonstrate that aGVHD risk, and in certain settings TRM, is lowest in UHR ...
Computational HLA typing has surged as a cost-effective strategy to uncover questions regarding the evolution of the HLA system, enabling immunogenic characterization from ancient DNA (aDNA) data.
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Allogeneic haematopoietic cell transplantation (HCT) is a potentially curative treatment for both malignant and non-malignant hematologic disease, as well as some immunologic and metabolic disorders.