The innate immune response is the body’s first line of defence, utilising specialised protein complexes known as inflammasomes to detect pathogenic insults and cellular damage. These multi‐protein ...
“These are the first data to link ASC speck assembly, NLRP1 inflammasome activation, and alpha-synuclein aggregation in neurons of Parkinson’s disease patients,” said Stephen C. Glover, ZyVersa’s ...
ZyVersa Therapeutics, in collaboration with the University of Miami Miller School of Medicine and with support from the Michael J. Fox Foundation, has published promising data on its inflammasome ASC ...
Researchers at the University of Washington and Fred Hutch found that CARD8, an inflammasome sensor, detects HIV-1 in macrophages during cell-to-cell viral transmissions from infected T cells. HIV can ...
New research from RCSI University of Medicine and Health Sciences has explained how the body’s internal clock influences the inflammatory process of the immune system. The findings describe how immune ...
NEWTON, Mass.--(BUSINESS WIRE)--Inflammasome Therapeutics (https://www.inflam.com/), a clinical-stage biotech company developing novel, first-in-class dual ...
This new article publication from Acta Pharmaceutica Sinica B, discusses how an anti-complement homogeneous polysaccharide from Houttuynia cordata ameliorates acute pneumonia with H1N1 and MRSA ...
BGE-102 has the potential for therapeutic retinal exposure with oral delivery, reducing treatment burden in ocular indications currently treated with intravitreal therapies Growing preclinical and ...
Study supported by the Michael J. Fox Foundation through a grant awarded to ZyVersa and leading inflammasome experts at University of Miami Miller School of Medicine who conducted the study. Parkinson ...