Researchers compared three different drug delivery models based on ionic liquids. Scientists have developed a powerful API-IL concept to access structural diversity and dual-action pharmaceuticals.
This statement is generally false. Covalent compounds tend to have lower melting and boiling points compared to ionic ...
A covalent bond is formed when two atoms share one or more pairs of electrons to achieve a stable electron configuration.
One class of drugs that has shown promise in treating diseases ranging from lung cancer to COVID-19 are targeted covalent inhibitors (TCIs). These small molecule drugs form covalent bonds with their ...
A structure of the drug ibrutinib. The drug ibrutinib makes a covalent bond to Bruton's tyrosine kinase, an important cancer target. Credit: RCSB PDB/Yang H. Ku Enticing atoms to share their electrons ...
In a recent study posted to the bioRxiv* preprint server, researchers developed covalent nanobodies (single-domain antibodies) to neutralize severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2 ...
Ionic bonds are formed between a metal and non-metal, for example sodium chloride. An atom of sodium will lose an electron and form a positive ion. An atom of chlorine will gain an electron and form a ...
The human organism is composed of numerous types of molecules, both simple and complex, and all fundamental processes in a living body occur in water solutions. Therefore, for a drug to work, it must ...
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