The 24-year-old Guerendo was a fourth-round pick in the 2024 NFL draft. He transferred to Louisville for the 2023 season after spending five years at Wisconsin. During his final year he rushed for 810 yards and 11 touchdowns, while adding 234 yards on 22 receptions. He averaged 6.0 yards per carry during his college career.

San Francisco 49ers running back Jordan Mason is going on injured reserve, head coach Kyle Shanahan announced.

NFL Week 14 odds, picks, predictions, TV channel, streaming information for Sunday football game between Chicago Bears and San Francisco 49ers.

Patrick Everson breaks down the football weekend that was, including how the 49ers' struggles impacted the books, and some mixed reactions after UM stunned Ohio State.

San Francisco 49ers running back Christian McCaffrey will not need surgery on his injured right knee but he will miss the rest of the regular season.

The San Francisco 49ers running back injured the PCL in his knee, an MRI confirmed Monday. San Francisco plans to place McCaffrey on injured reserve. He is expected to miss six weeks. Head coach Kyle Shanahan announced the news during his Monday press conference.

Four NFL games on Thanksgiving and Black Friday kicked off Week 13 action, and the full schedule continues on Sunday, Dec. 1, 2024 and Monday with more big watch and wager action. SNF 49ers-Bills and MNF Browns-Broncos stats,

Head coach Kyle Shanahan shared the latest injury and team updates emerging from the San Francisco 49ers Week 13 matchup versus the Buffalo Bills.

Hall of Fame wide receiver Randy Moss revealed he’s dealing with a health issue and asked fans to pray for him and his family.

Parts of the Great Lakes region are seeing new snow and face the prospect of even more this week after U.S. travelers battled harsh weather to get home after Thanksgiving.