Durham, NC - Researchers have traced the breakdown of nitroglycerin into the vasodilator nitric oxide (NO) to an enzymatic process centered in the mitochondria of vascular smooth muscle cells. Their ...

Durham, NC - The action of a mitochondrial enzyme seems necessary for nitroglycerin vasodilation, and inactivation of this enzyme explains how nitroglycerin tolerance can occur with long-term ...

Continuous transdermal nitroglycerin did not lead to sustained improvements in hot flashes for perimenopausal and postmenopausal women, the randomized FRAN trial showed. Over 5 weeks, the estimated ...

Administering nitroglycerin during the course of transradial cardiac catheterization fails to reduce the risk of radial artery occlusion, according to results from the large PATENS trial. Whether ...

Please provide your email address to receive an email when new articles are posted on . Transdermal nitroglycerin and placebo had similar outcomes for hot flash ...

Before the advent of nitroglycerin 130-odd years ago, the only explosive in use was black gunpowder. The Swedish industrialist Alfred Nobel developed nitroglycerin, and its spin-off, dynamite, at a ...

Vasodilation refers to a widening of the blood vessels within the body. This occurs when the smooth muscles in the arteries and major veins relax. Vasodilation occurs naturally in response to low ...