Many diseases are caused by dysfunctional gene expression that leads to too much or too little of a given protein. Efforts to ...

Engineers and biologists at Dartmouth College have found that, just like word order affects meaning in a sentence, the ...

Genomics company, Integrated DNA Technologies, is rewriting the future of genomics, pioneering new innovations in a bold move ...

The use of microarrays to analyse gene expression ... whether based on oligonucleotides or cDNA, are highly capable of generating long lists of genes with altered expression, but they provide ...

Hathway’s technology uses natural epigenetic processes to dial gene activity up or down, rather than rewriting the genetic ...

since control of the timing, location, and amount of gene expression can have a profound effect on the functions (actions) of the gene in the organism.

Therapeutic oligonucleotides act on different stages of pathological gene expression. Standard schematic of oligonucleotide activities in pathogenesis disease progression. Decoys bind to transcription ...

The main steps involved and limitations of microarray analysis will be encountered. Two stages can be distinguished in microarray experiments: a pre-microarray experiment phase (tissue handling ...

Getting therapeutic drugs past the blood-brain barrier has long been a major challenge in treating brain diseases. Now, researchers have explored how cholesterol-modified heteroduplex oligonucleotides ...

Although the contraption sounds unusual, it relies on combining two well-known technologies: optogenetics, which uses light-sensitive proteins to control gene expression, and an EEG-based ...

Epigenetics is the study of various heritable alterations that control gene expression without changing the DNA sequence. 1 The name epigenetics comes from the Greek prefix “epi”, which means on top ...