Getting therapeutic drugs past the blood-brain barrier has long been a major challenge in treating brain diseases. Now, researchers have explored how cholesterol-modified heteroduplex oligonucleotides ...

Getting therapeutic drugs past the blood-brain barrier has long been one of medicine's most difficult challenges, limiting ...

Genomics company, Integrated DNA Technologies, is rewriting the future of genomics, pioneering new innovations in a bold move ...

The use of microarrays to analyse gene expression ... whether based on oligonucleotides or cDNA, are highly capable of generating long lists of genes with altered expression, but they provide ...

Many diseases are caused by dysfunctional gene expression that leads to too much or too little of a given protein. Efforts to ...

since control of the timing, location, and amount of gene expression can have a profound effect on the functions (actions) of the gene in the organism.

The main steps involved and limitations of microarray analysis will be encountered. Two stages can be distinguished in microarray experiments: a pre-microarray experiment phase (tissue handling ...