The degree of complexity and crossover within MAPK signaling, and also shifts in pathways such as nuclear factor κB signaling, could also explain the modest effect of p38 inhibitors. The p38α ...
The p38 MAPK regulates intracellular signaling pathways in response to environmental stress. Its inhibition blocks the production of inflammation-causing cytokines, such as IL-1β and TNF-α ...
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