At later maturation stages, PDGF signaling plays a role in tissue remodeling, cellular differentiation, and key inductive events involved in patterning and morphogenesis. Beyond stimulating ...

Now, researchers have discovered that inhibiting PDGF-CC/PDGFRα signaling can reduce scarring in the brain and improve ...

[64] Inhibition of PDGF signaling (using anti-PDGFR or RTK) in corneal neovascularization prevents mural cell recruitment to new vessels and causes dropout in established vessels, with combination ...

platelet-derived growth factor receptor (PDGFR) and bcr–abl. Because of the crucial role of the PI3K pathway in normal cell growth and in the cellular response to stress, the main challenge to ...