Objective: To review drug interaction studies of glucagon-like peptide-1 receptor agonists (GLP-1RAs) and concurrent oral medications. Data Sources: PubMed was searched (to December 5, 2011) using the ...
Focusing on pharmacokinetic and pharmacodynamic mechanisms, Dr Erin C Berthold discusses the interactions between botanical ...
Pharmacodynamic interactions alter pharmacologic efficacy of a drug, although drug plasma levels remain unaltered. 2 This has an impact on either the pharmacologic efficacy or on the magnitude of side ...
Drugs that target opioid receptors sometimes have severe side effects. Thousands of people around the world die every day from overdoses involving opioids such as fentanyl. An international team of ...
We conducted a retrospective analysis of individuals who had been tested for CYP genetics to determine the prevalence of DDIs, DGIs and DDGIs in the sample. Approval for the study was obtained from ...
Pemetrexed (P) and bevacizumab (B) in patients (pts) with recurrent or metastatic head and neck squamous cell carcinoma (HNSCC): updated results of a phase II trial No significant financial ...
Proceedings of the National Academy of Sciences of the United States of America, Vol. 87, No. 24 (Dec., 1990), pp. 9751-9755 (5 pages) The regulation of osteocalcin gene expression by ...
SAN JOSE, Calif., Dec. 14, 2023 (GLOBE NEWSWIRE) -- Rani Therapeutics Holdings, Inc. (“Rani Therapeutics” or “Rani”) (Nasdaq: RANI), a clinical-stage biotherapeutics company focused on the oral ...
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Calcium-sensitive switch boosts the efficacy of cancer drugs
Cancer-fighting antibody drugs are designed to penetrate tumor cells and release a lethal payload deep within, but too often ...
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