Glucose is not only a major nutrient regulator of insulin secretion, but also impacts on gene expression in beta-cells. Using a mouse model of beta-cell-specific knock-out of Pdha1 gene which encodes ...

WE have recently reported 1 that the oxidation of pyruvate by finely ground preparations of pigeon's brain is catalysed by fumarate and adenylic acid (or adenosine triphosphate). The effect of ...

Recent research has indicated that in the process of generating energy, leukemic cells use a cellular pathway known as fatty acid oxidation, rather than pyruvate oxidation, as had been previously ...

Indications: Measured enzymatically in blood or CSF as an index of impaired pyruvate metabolism due to defects of glucose oxidation (fed state) or gluconeogenesis (fasted). The ratio of lactate to ...

This is a preview. Log in through your library . Abstract We have studied the effects of ATP and ADP on the oxidation of malate by coupled and uncoupled mitochondria prepared from etiolated hypocotyls ...

Researchers at the University at Buffalo, led by Dr. Mulchand Patel and also at Lawson Health Research Institute and Western Ontario, London, Canada, led by Dr. David Hill, collaboratively evaluated ...