Thus, targeting epigenetic factors that change the accessibility of the chromatin could help regulate stem cell lineage plasticity and restore proper stem cell function. We started off by studying the ...

Now, new research demonstrates that once stem cells have entered this state, known as lineage plasticity, they cannot ...

Questions regarding the plasticity in differentiation have led to a debate about the potential of cells to 'transdifferentiate' or to 'reprogramme' themselves. These issues can be addressed not ...

differentiation and adult stem cell plasticity. For example, Ron McKay and coworkers at the National Institute of Neurological Disorders and Stroke, demonstrated that they can direct murine ESCs to ...

"Cell plasticity" refers to cancer cells' ability to alter their phenotypes in response to changes in their microenvironment, ...

Cells navigating in complex microenvironments frequently encounter narrow spaces that physically challenge migration.

NG2 cells, or polydendrocytes, are a population of CNS cells that are distinct from neurons, mature oligodendrocytes, astrocytes and microglia. They can be identified by the expression of the NG2 ...

The axon initial segment (AIS) is where nerve signals begin, and its adaptability is key to brain function. Scientists have found that the AIS changes in response to activity levels, helping neurons ...

This dynamic period of early development sees embryonic cells displaying remarkable plasticity, yet the molecular mechanisms and factors that regulate this plasticity remain unclear. Research in ...