The transplantation of allogeneic skin grafts is associated with a potent inflammatory immune response leading to the destruction of donor cells and the rejection of the graft. Shortly after ...

Karl Koehler builds inner ear and skin organoids from human stem cells to model their development in health and disease.

Researchers have successfully developed nerve grafts, currently being trialed as a treatment for Parkinson’s disease, that ...

A new procedure enables researchers to generate skin from undifferentiated cells. As well as a tool for studying how skin develops, these skin organoids could be used as a source for grafts as ...

It is important because identifying skin stem cells and learning ... the outer root sheath should provide the stem cells necessary for long-term graft survival in these, or more sophisticated ...

Following placement of skin allografts, donor DCs, often referred to as passenger leukocytes, migrate out of the graft through lymphatic vessels and infiltrate the recipient's draining lymph nodes ...