Among other functions, the NK cells (natural killers, a type of lymphocyte forming part of the immune system) have the capacity to detect and eliminate cancer cells. But in some cases they cannot ...

Among these factors, the transforming growth factor (TGF)-β family is ... a process named epithelial–mesenchymal transition or transformation (EMT), and in this way they contribute to the ...

The epithelial-to-mesenchymal transition (EMT) process is crucial for liver wound healing and cancer metastasis. TGF-β is a potent inducer of EMT, promoting cell migration and invasion.

Fibrosis is triggered by the activation of the TGF-β signaling pathway leading to increased fibroblast proliferation, epithelial–mesenchymal transition (EMT) and/or increased remodeling of ECM ...

They offer innovative diagnostic and therapeutic options. As an example, modulation of TGF-β/BMP-7 ratio changes the rate of EMT, and so the simultaneous determination of these parameters and of ...