Schematic representation of different strategies targeting TGF-β signaling for liver fibrosis therapy. TGF-β signaling inhibitors hold important therapeutic potential for hepatic fibrosis. Although ...
Henan Medinno Pharmaceutical Technology Co. Ltd. has synthesized TGF-β receptor type-1 (TGFBR1; ALK5; SKR4; TβR-I) inhibitors reported to be useful for the treatment of cancer, aging, arteriosclerosis ...
Investigating the association of WNT pathway dysregulation and young-onset colorectal cancer. This is an ASCO Meeting Abstract from the 2024 ASCO Gastrointestinal Cancers Symposium. This abstract does ...
Data presented at ESMO 2025 show INCA33890, a TGFβR2×PD-1 bispecific antibody, has the potential to be an effective treatment in microsatellite stable (MSS) colorectal cancer Planned initiation of ...
Toxicity profile of temozolomide in the treatment of 300 malignant glioma patients in Korea. This is an ASCO Meeting Abstract from the 2012 ASCO Annual Meeting I. This abstract does not include a full ...
GHENT, Belgium--(BUSINESS WIRE)--Agomab Therapeutics NV (‘Agomab’) today announced positive clinical results from its Phase 1 study evaluating AGMB-129, an oral gastro-intestinal (GI)-restricted small ...
A team led by scientists at King's College London, in collaboration with national and international partners, has discovered ...