The "TGFb inhibitors – Pipeline Insight, 2021" drug pipelines has been added to ResearchAndMarkets.com’s offering. The companies and academics are working to assess challenges and seek ...

The transforming growth factor-β (TGF-β) superfamily of ligands has a pivotal role in the regulation of a wide variety of physiological processes from development to pathogenesis. Since the ...

New study results suggest that integrin inhibitors have the potential to both prevent infection with SARS-CoV-2, including the Delta and Omicron variants, and to decrease TGF-β levels, resulting ...

Transforming growth factor (TGF)-β signaling is an attractive therapeutic target as it is deregulated in many cancers. But challenges remain around developing inhibitors that can specifically block ...

Presentations at CICON on Friday, Sep. 27, at 1:00 PM and 6:30 PM CEST and at ESMO on Saturday, Sep. 28, at 12:00 PM CEST AVID200 is a first-in-class, rationally designed inhibitor of TGF-beta 1 ...

A mouse study suggests that using an inhibitor of transforming growth factor beta (TGF-beta) alongside primary therapy for cancer has clinical benefits, reducing metastases and radiation side effects.

PERTH, Australia and TAIPEI and SHANGHAI, Oct. 20, 2021 /PRNewswire/ -- GenFleet Therapeutics, a clinical-stage biotechnology company focusing on ...

Recent scientific, clinical breakthroughs and high-profile industry deals have reignited the race to find the next blockbuster TGF-ß inhibitor for immuno-oncology applications.

This created a new opening for cancer therapy, the researchers thought. If cold tumors were treated with a TGF-Beta blocker, it would open the door for immunotherapy to drive tumor-killing lymphocytes ...

By revealing that the TGF-beta pathway plays a protective role against uterine cancer, this work has significantly advanced our understanding of the disease and opened novel avenues for future ...