In some non-small cell lung cancers (NSCLCs), changes to the RET gene (known as RET fusions) can drive tumor growth. In a ...

Lung cancer in never-smokers exhibits distinct biological characteristics, often leading to late-stage diagnoses due to lack of screening. Targeted therapies, guided by molecular testing, offer ...

Combination therapy is essentially a one-two punch at cancer—sometimes with multiple punches. For people with lung cancer, it ...

Targeted therapies are cancer medications that work more selectively than standard chemotherapy medications. They do this by targeting specific molecules or genetic changes in cancer cells in order to ...

Targeted therapies are a type of medicine used to treat cancer. They work differently than standard chemotherapy. Instead of killing all fast-growing cells or keeping them from dividing, targeted ...

Selecting the right targeted therapy or clinical trial for each cancer patient is one of modern oncology’s greatest challenges. Each tumor carries a unique combination of four to five actionable ...

A recent study led by Paul DeCaen, Ph.D., associate professor of Pharmacology, has identified novel molecular mechanisms by which genetic mutations in the PKD2 gene cause the most common form of ...

Lung cancer is a complex disease that can be very hard to treat. It often grows quietly and spreads before it is discovered.

IgA nephropathy (IgAN), or Bergers disease, is a kidney condition that occurs when abnormal immunoglobulin A (IgA) antibodies trigger inflammation in the kidneys.Until recently, treatment for IgAN ...