Testosterone synthesis in testicular Leydig cells is orchestrated by a tightly regulated sequence of signalling events, cholesterol trafficking and enzymatic conversions. Upon luteinizing hormone (LH) ...

The COVID-19 virus hijacks the machinery of testicular cells that produce the hormone testosterone in order to replicate. It also appropriates the metabolic pathways of these cells and cholesterol, a ...

Cholesterol often gets a bad reputation, but the story is more nuanced than “cholesterol = bad.” Sure, too much LDL cholesterol in your blood can be harmful for your heart, but the cholesterol your ...

Direct assessment of Leydig cell function in childhood cancer survivors has been limited. The objectives of this study were to describe the prevalence of and risk factors for Leydig cell failure (LCF) ...