The Hoosiers jumped out to an early lead when quarterback Kurtis Rouke handed the ball off to Ty Son Lawton, who scored the game's first touchdown. However, this lead was short-lived, as the Buckeyes' defense quickly took control.

Ohio State remains firmly in the hunt for a first-round CFP bye, while Indiana's hope for a berth took a massive hit

Indiana lost 38-15 to OSU at Ohio Stadium with notable miscues in all three phases. The Buckeyes scored 31 consecutive points after IU scored on its opening possession while holding the Hoosiers to less than 200 yards — they traded touchdowns during the game's final two minutes.