On Tuesday, a Food and Drug Administration (FDA) advisory panel concluded that one of the key ingredients in many over-the-counter (OTC) decongestant medications doesn’t work. The ingredient, ...

The U.S. Food and Drug Administration (FDA) on Thursday released a warning over serious health issues, and even death, tied to higher than recommended doses of over-the-counter antihistamine drug ...

An Ohio family is sharing a new warning about the viral Benadryl challenge on TikTok after their 13-year-old son died from an overdose trying to do it, the family said. The dangerous stunt calls for ...

A new alarming trend on TikTok is prompting teens to take dangerously high amounts of Benadryl — and experts are warning the activity could be fatal. In July, Cook Children’s Medical Center in Texas ...

The “Benadryl challenge” is a dangerous social media fad on the app TikTok that led to the death of a 15-year-old Oklahoma teen last week, and the hospitalization of at least three Texas teenagers in ...

Some allergy specialists are questioning whether one of the most familiar and oldest antihistamines, diphenhydramine, needs to be retired in favor of second-generation drugs that have fewer side ...

Hydroxyzine (whose brand names include Vistaril) and Benadryl (the brand name of diphenhydramine) are both first-generation antihistamines and share many similarities, including sedating side effects.

If you're looking for relief from cold or allergy symptoms, you'll find whole aisles of over-the-counter options – including Benadryl. But is it safe to take while you're pregnant? As with any ...