A new study published in The New England Journal of Medicine showed that for high-risk patients with pulmonary arterial ...

Right ventricular hypertrophy, right ventricular systolic pressure, and vascular remodeling—all complications of pulmonary hypertension—were reduced as compared with controls that did not ...

Serotonin can promote both pulmonary vasoconstriction and pulmonary vascular remodeling and is thought to be involved in the pathobiology of PAH. A polymorphism in the serotonin transporter (SERT ...

PH is a common consequence of ILD because of vascular and parenchymal remodeling, with the highest rate seen among individuals who have idiopathic pulmonary fibrosis. Most of these cases are ...

Transition from healthy to diseased state is a cell-type-specific process, influenced by neighboring cells and resulting in functionally meaningful differences between pulmonary artery adventitial ...

In pulmonary hypertension, a combination of metabolic and mechanical dysfunction leads to irreversible vascular damage.

Pulmonary arterial hypertension (PAH) is a rare and severe lung disease with a life-threatening prognosis. After several positive trials, a recent study has confirmed the efficacy of a biotherapy, ...

cholesterol the role of natriuretic peptide signaling and mineralocorticoid receptor antagonism in protecting against adverse remodeling in the pressure-overloaded heart the molecular pathogenesis of ...

Back to Healio In this episode, we dive into the early therapies and how our understanding of vascular physiology drastically changed the management of pulmonary hypertension.