Right ventricular hypertrophy, right ventricular systolic pressure, and vascular remodeling—all complications of pulmonary hypertension—were reduced as compared with controls that did not ...

In regenerative science, B7-33's potential to influence fibroblast activity and collagen turnover suggests possible implications for tissue repair and wound healing. Given that fibrosis is often a ...

A new study published in The New England Journal of Medicine showed that for high-risk patients with pulmonary arterial ...

Serotonin can promote both pulmonary vasoconstriction and pulmonary vascular remodeling and is thought to be involved in the pathobiology of PAH. A polymorphism in the serotonin transporter (SERT ...

"We know that during the remodeling process fibroblasts are activated," said Cheng Hong, MD, Ph.D., pulmonary vascular medicine specialist at the First Affiliated Hospital of Guangzhou Medical ...

In PAH, these remodeling processes within these arterioles ... exercise tolerance and pulmonary vascular resistance. Due to this superiority, the study was terminated prematurely—a continuation ...

cholesterol the role of natriuretic peptide signaling and mineralocorticoid receptor antagonism in protecting against adverse remodeling in the pressure-overloaded heart the molecular pathogenesis of ...

In pulmonary hypertension, a combination of metabolic and mechanical dysfunction leads to irreversible vascular damage.

Pulmonary arterial hypertension (PAH) is a rare and severe lung disease with a life-threatening prognosis. After several positive trials, a recent study has confirmed the efficacy of a biotherapy, ...

cholesterol the role of natriuretic peptide signaling and mineralocorticoid receptor antagonism in protecting against adverse remodeling in the pressure-overloaded heart the molecular pathogenesis of ...