A novel inflammasome inhibitor derived from HIV antivirals has reversed established neurological deficits in a preclinical MS ...
Spatial proteomics is becoming stronger. But how can researchers turn complex, high-dimensional spatial data into meaningful insights – and which challenges remain hardest to solve? Prostate cancer ...
Researchers at UC Berkeley have used long-term human brain organoids to show that hyperreactive astrocytes may drive the ...
City of Hope researchers have developed a modular 'plug-and-play' CAR T-cell platform that enables post-infusion ...
A preclinical study published in Myeloid Cells reports that AS01, a vaccine adjuvant system, can induce trained immunity in human monocytes and reduce tumour growth in selected mouse cancer models.
Scientists at Wake Forest University School of Medicine have uncovered a previously unrecognised cancer-intrinsic role for ...
Scientists at National Jewish Health have identified oestrogen receptor alpha as a potential therapeutic target for ...
A bacterial enzyme produced by Bacteroides vulgatus has been shown to inactivate the intestinal hormone GLP-2, disrupting gut ...
A nasal spray using extracellular vesicles derived from the amniotic membrane has shown promise against Alzheimer's disease, ...
Why do promising CNS therapies struggle to translate into patients? Three experts explore how biomarkers can track ...
Humanised antibodies targeting the voltage-gated sodium channel Nav1.7 have demonstrated prolonged suppression of neuropathic ...
Researchers at the University of Basel have screened more than 1,600 compounds using a biobank of 35 hepatocellular carcinoma ...
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