Researchers describe a novel acidic niche within lymph nodes that plays an integral role in regulating T cell activation. In the fight against cancer, the immune system is the first line of defense.

People with leukemia may have high levels of uric acid. If large numbers of cancer cells die rapidly, they release significant amounts of uric acid into the bloodstream, which the kidneys are ...

Dr. Bhatia and colleagues from UAB, University of Zurich, and Osaka University discovered that TKIs (drugs that most leukemia patients are treated with) do not eliminate disease-propagating leukemic ...