News

Unraveling the G4 knot: How cells untie DNA to protect the genome
Not all DNA looks like the familiar twisted ladder. Sometimes, parts of our genetic code fold into unusual shapes. One such ...
GEN - Genetic Engineering and Biotechnology News6d
Knot a Problem: Mechanism Found for DNA Loop Control
Disrupting the G-loop cycle causes transcriptome dysregulation and genome instability, revealing key role in cell survival and homeostasis.
RNA has newly identified role: Repairing serious DNA damage to maintain the genome
Your DNA is continually damaged by sources both inside and outside your body. One especially severe form of damage called a ...
“Jumping Genes” Found Hijacking Cell Division To Rewrite Human DNA
LINE-1, a "jumping gene" making up 20% of the genome, invades DNA during cell division using protein-RNA clusters, offering ...
Science Daily1h
Microscopic heist: How lung bacteria forge weapons to steal iron and survive
Researchers investigating the enigmatic and antibiotic-resistant Pandoraea bacteria have uncovered a surprising twist: these ...
Acurx Pharmaceuticals, Inc.: Acurx Announces Publication in Lancet Microbe of Phase 2b Clinical Trial Data for Ibezapolstat in CDI
As previously reported, 15 out of 16 (94%) patients in Phase 2b in the Per Protocol Population experienced Clinical Cure (CC) and all 15 of 15 (100%) remained free ...
pharmaphorum2d
GSK antibiotic gepotidacin clears phase 3 gonorrhoea trial
Gepotidacin inhibits bacterial DNA replication by a novel mechanism of action and binding site, blocking two different type II topoisomerase enzymes, and has shown activity in the lab against ...
C&EN4d
Mechanism-Based Inhibition of an Essential Bacterial Adenine DNA Methyltransferase: Rationally Designed Antibiotics
Article Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to ...