This study presents a system for delivering precisely controlled cutaneous stimuli to freely moving mice by coupling markerless real-time tracking to transdermal optogenetic stimulation, using the ...

“I was petrified.” Today, after a complete revamp of her lifestyle and overall health, Ashford’s struggles with retrieving words have eased, while measures of amyloid and tau proteins and ...

High serum type I interferon (IFN) scores, measured through six chemokines, correlated with poorer lung function and health-related quality of life in patients with diffuse cutaneous systemic ...

The therapies encourage cleaning cells called microglia to attack the clumps of amyloid-beta proteins that are thought to be involved in neurodegeneration. Microglia responses to amyloid beta can lead ...

Department of Neuroscience, Developmental, and Regenerative Biology, University of Texas at San Antonio, 1 UTSA Circle, San Antonio, Texas 78249, United States ...

Scientists at the University of Toronto studying the hermaphroditic worm Caenorhabditis elegans found that amyloid-like structures—proteins often associated with diseases like Alzheimer’s ...

Nearly one million people worldwide are plagued annually by cutaneous leishmaniasis, a devastating skin infection caused by the Leishmania parasite. Predominantly affecting vulnerable populations ...

The immunoassay measures the ratio of ptau-217 and beta amyloid 42, two distinct biomarkers of Alzheimer's, according to the Wednesday announcement. The Global CEO Initiative on Alzheimer’s Disease ...

Please discuss the class and complete drug profile of amyloid-targeting therapies for Alzheimer disease, including their mechanisms of action, efficacy, and safety profiles.

CD47 is found to play a pivotal role in this immunosuppression by inducing the production of amyloid-β (Aβ), which interacts with CD74 on B cells, leading to B-cell suppression and subsequent adaptive ...