BARCELONA -- The oral drug deucravacitinib (Sotyktu) passed what is probably its final test as a treatment for psoriatic ...

Called enpatoran, the agent targets the Toll-like receptor (TLR) species 7 and 8. Some 50%-60% of patients with systemic ...

Cohort A focused on patients with CLE or SLE with active lupus rash and evaluated organ-specific disease activity using the Cutaneous Lupus Erythematosus Disease Area and Severity Index Activity ...

Immunovant faces high R&D costs, limited cash runway, and unproven clinical edge despite pipeline progress and deeper IgG ...

These manifestations are often part of the systemic activity or flare, which can be painful and have a considerable impact on quality of life,” said principal investigator Prof. Eric Morand, from ...

Merck KGaA has shed more light on the failure of its lupus drug in one cohort of patients, while pointing to secondary ...

Cohort B of the Phase 2 study indicates all doses of enpatoran were associated with higher BICLA response rates compared with placebo, though the ...

Topical calcineurin inhibitors in cutaneous lupus erythematosus In the management of cutaneous lupus erythematosus (CLE), topical calcineurin inhibitors have recently been established as the ...

The Johns Hopkins Department of Dermatology is seeking volunteers with cutaneous lupus to participate in a research study ...

Few reports studied key downregulated pathways and mediators. Using unbiased proteomic technique, we have previously identified IL-16 as a key cytokine in cutaneous lupus erythematosus (CLE), and ...