Biology lectures teach students that when a cell’s replication machinery comes together, DNA polymerase takes off down the double-helix like a car on a highway ...

Scientists found a compound that appears to counter common mutations behind POLG-related diseases, rare conditions that harm ...

Scientists have yet to identify a polymerase that can add bases to the 5' ends of DNA strands. The fragments of newly synthesized DNA along the lagging strand are called Okazaki fragments ...

Forensic DNA profiling uses polymerase chain reaction (PCR) to amplify short tandem repeats (STRs), which are highly variable DNA regions, typically with four repeating bases. This variability helps ...

PCR genetic analysis has been in the spotlight since COVID-19, but light is now further facilitating PCR-free methods. Osaka ...

The POLG gene regulates the production of DNA polymerase gamma, an enzyme that copies mitochondrial DNA. Without it, the mitochondria cannot function normally and, as a result, fail to provide the ...

The researchers focused on the three-protein CST complex and the DNA polymerase α/primase (PP) complex, which are important for the proper upkeep of telomeres. "We found that DNA polymerase α is ...

This gene encodes a protein in mitochondria, called DNA polymerase gamma (pol γ), which is needed to replicate and repair the ...

The Company's approach is to develop antibiotic candidates with a Gram-positive selective spectrum (GPSS®) that blocks the active site of the Gram-positive specific bacterial enzyme DNA ...

This patent relates to DNA Polymerase IIIC Inhibitors, including compositions-of-matter. This is the latest in the series of granted patents and pending patent applications that Acurx has file ...