Lipid metabolism has emerged as a central player in the progression and therapy resistance of breast cancer, particularly the aggressive subtype ...

Gonadorelin, a synthetic analog of the gonadotropin-releasing hormone (GnRH), has garnered attention for its intriguing ...

Results of the study, conducted in partnership with Xi'an Jiaotong University Health Science Center, are published in Signal Transduction ... inhibit the inflammatory pathways driving ...

BPA is known for having estrogenic properties, which means it can disrupt typical estrogen signaling and lead to downstream hormonal dysfunction. EDCs can also: block natural hormones from doing ...

[23] Estrogens are known to drive physiological selection of Th1 or Th2 pathways. A perturbation in immune receptor signaling may underlie the increase in autoimmune phenomena in the elderly ...

But fat also acts as a hormone factory, containing the enzyme aromatase, which converts testosterone into estrogen ... the mTOR and IIS pathways—cellular processes that speed up aging—go ...

One of the best studied signalling routes is the mitogen activated protein (MAP) kinase signal transduction pathway which plays a crucial role in many aspects of immune mediated inflammatory responses ...

Their findings, which were published in Science Advances, also offer new insights into 2'3'-cGAMP's role in cell migration and how the newly identified 2'3'-cGAMP/Rab18/FosB signaling pathway ...

Menopause doesn’t directly cause a rash, but lowering estrogen levels can contribute to dry, itchy skin. Menopause can bring about many physical changes. In addition to changes in menstruation ...

Further important areas of research are signal processing and transmission, the regulation of protein breakdown and how cancer evolves. The researchers also want to find out what the actual protein ...