NCAM-180 is a structural molecule that mediates cell-cell adhesion, resulting in tissue stabilization. It has been proposed as a tumor suppressor in colon carcinoma.

As in the development of many human cancers, in a transgenic mouse model of β-cell carcinogenesis (Rip1Tag2), expression of neural cell adhesion molecule (NCAM) changes from the 120-kDa isoform ...

Cell adhesion molecule L1, a key member of the immunoglobulin superfamily, plays a pivotal role in the development and maintenance of the nervous system. Its functions extend from guiding neuronal ...

During cell adhesion, the extracellular domain binds to another cell adhesion molecule. In response, the transmembrane region rearranges the structure of the intracellular domain—a process ...

Over the years, deficits in neural cell adhesion molecules have been implicated in schizophrenia and other psychiatric disorders. One adhesion molecule, neurexin, ...

A twisted cell-cell adhesion molecule complex structure revealed by single-molecule fluorescence microscopy and high-speed atomic force microscopy. National Institutes of Natural Sciences.

The team studied a protein in the brain called neural cell adhesion molecule 2, or NCAM2 -- one of a family of molecules that physically connects the membranes of synapses and help stabilise these ...

Regulated Expression of the Neural Cell Adhesion Molecule L1 by Specific Patterns of Neural Impulses. Kouichi Itoh, B. Stevens, M. Schachner and R. D. Fields in Science, Vol. 270, pages 1369¿1372 ...

Parkinson’s disease is a neurodegenerative condition characterized by symptoms such as tremor, impaired balance, and slowness of movement. New research from Spain, however, may have found a way ...

A small molecule called ISRIB that was identified at UC San Francisco can reverse the neuronal and cognitive effects of concussion in mice weeks after an injury occurred, new research has found. ISRIB ...