Patients with systemic sclerosis and calcinosis cutis may have a higher tendency for bone-resorbing cell activity, suggesting ...

The new work has taken female mice into space to live on board the International Space Station (ISS) for 37 days and observed ...

Historical trends and future projections of the number of people with overweight and obesity suggest alarming parallel ...

Two of these candidate genes, CSF1 and TNFRSF11A (located at 1p13 and 18q21, respectively), code for proteins already known to be associated with Paget disease pathology and osteoclast function.

The research suggests that NKD2 not only promotes osteoblast differentiation but also inhibits adipocyte formation and osteoclast activity, positioning it as a potential therapeutic target for ...

Studies report an increase in osteoporosis of 8% to 11% in transgender women compared to their cisgender male counterparts before initiating hormone replacement therapy (HRT). 1 Over the past 25 years ...

“We found that this treatment primed osteoclast precursors to differentiate into osteoclasts more readily if presented with an inflammatory challenge like arthritis,” Triantafyllos Chavakis, ...

Osteoporosis, a condition that weakens bones, can be managed with lifestyle changes. Adequate calcium, vitamin D, ...

Jan. 21, 2025 — The discovery of a family with sequence similarity 102 member A (Fam102a) protein as a novel bone remodeling factor that regulates both osteoclast and osteoblast differentiation ...