Programming bacteria to have therapeutic functions will require a toolbox ... A synthetic switch was constructed by fusing DH to a PDZ domain and a PDZ substrate that can be phosphorylated by ...

A medical breakthrough could result in the first treatment for rare but serious diseases in which genetic defects disrupt ...

Proper tuning requires understanding process characteristics, including time constants, deadtime, and open-loop gain. Load ...

Oscar-winning lyricist Sir Tim Rice has said he has not ruled out teaming up again with former musical partner Lord Andrew Lloyd-Webber to create a brand new musical, but warned it would have to ...

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Figure 3. Representative images of the E. coli proteome array assays with the Dylight™ 549 fluorescence-labeled Prc protein variants Prc (WT), K455A-Prc (K455A), and ΔPDZ-K455A-Prc (ΔPDZ-K455A). Among ...

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Additionally, no abnormality in karyotypes, metabolic screening, and the function of the thyroid glands was observed. However, the levels of growth hormone were obviously below normal, which remained ...

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Furthermore, we identified the polybasic motif in the C2B domain that facilitates SV release. Finally, we found that disruption of C1 and C2B membrane interaction in UNC-13S, the short isoform, leads ...