A synthetic switch was constructed by fusing DH to a PDZ domain and a PDZ substrate that ... binding RNA sensor with an RNA hairpin structure that acts as a temperature sensor to produce a circuit ...

We show here that these diverse peptide sequences bind with comparable affinities to the Numb PTB domain at a common binding site on the surface of the protein. The NMR structure of the Numb PTB ...

A medical breakthrough could result in the first treatment for rare but serious diseases in which genetic defects disrupt ...

Oscar-winning lyricist Sir Tim Rice has said he has not ruled out teaming up again with former musical partner Lord Andrew Lloyd-Webber to create a brand new musical, but warned it would have to ...

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Secondly, Simulation Interaction Diagram algorithm was used to analyze the RMSD of the alpha carbon atoms (Cα), the root mean square fluctuation (RMSF) of the residues, and secondary structure element ...

This cover highlights the article PLK1 inhibition delays mitotic entry revealing changes to the phosphoproteome of mammalian cells early in division by M. Gobran, P. Lenart and colleagues. HeLa Kyoto ...

Figure 3. Representative images of the E. coli proteome array assays with the Dylight™ 549 fluorescence-labeled Prc protein variants Prc (WT), K455A-Prc (K455A), and ΔPDZ-K455A-Prc (ΔPDZ-K455A). Among ...

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Institute of Physics, University of Pécs, Ifjúság útja 6, Pécs H-7624, Hungary Department of Theoretical Physics, University of Szeged, Tisza Lajos krt. 84-86, Szeged H-6720, Hungary Department of ...