In MASLD and MASH, TGF-β signaling contributes to hepatocyte lipid accumulation, cell death and fibrosis progression through both Smad and non-Smad pathways. In HCC, TGF-β and other TGF-β-SF cytokines ...

For instance, the team discovered that non-cancerous cells bordering cancer cells were in a unique state driven by transforming growth factor-beta (TGF-β) signaling, a critical pathway involved ...

Revised: This Reviewed Preprint has been revised by the authors in response to the previous round of peer review; the eLife assessment and the public reviews have been updated where necessary by the ...

The aim of this study was to delineate PI3K/mTOR signalling in response to TGF-β 1 stimulation of primary human lung fibroblasts (HLFs), and to investigate the role of this pathway in TGF-β 1 mediated ...

You are able to gift 5 more articles this month. Anyone can access the link you share with no account required. Learn more. The Town of Norway has posted the following roads, effective Wednesday ...

We discovered that CHRDL1 inhibits the epithelial-mesenchymal transition (EMT) in LUAD through the TGF-β pathway. Conclusion: CHRDL1 exerts a complex influence on cancer development and progression, ...

One of the best studied signalling routes is the mitogen activated protein (MAP) kinase signal transduction pathway which plays a crucial role in many aspects of immune mediated inflammatory responses ...

Graduate School, Hebei University of Traditional Chinese Medicine, Shijiazhuang 050091, P. R. China Department of Spleen and Stomach, First Affiliated Hospital of Hebei University of Traditional ...

Hospital of Stomatology, Guanghua School of Stomatology, Sun Yat-Sen University, Guangzhou, Guangdong 510055, China Guangdong Provincial Key Laboratory of Stomatology, Sun Yat-Sen University, ...

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