Bicara Therapeutics shows potential to reshape cancer care with ficerafusp alfa and robust funding post-IPO. Find out why ...

A new therapy that first made headlines in 2021 is now showing potential to heal human cartilage. Developed by scientists at Northwestern University, the technique was initially created to repair ...

Objective To determine whether a chemokine receptor type 2 antagonist, DMX-200 (repagermanium), in combination with an angiotensin receptor blocker, candesartan, improves clinical outcomes in people ...

1Children’s Research Institute and the Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas. 10Howard Hughes Medical Institute, UT Southwestern Medical Center, ...

Department of Clinical Pharmacology, The Second Hospital of Anhui Medical University, Hefei 230601, China Clinical Research Unit, Changhai Hospital, Naval Medical University, Shanghai 200433, China ...

NKG2D, NK Group 2, Member D; LILRB1/2, leukocyte immunoglobulin-like receptor B1/2 ... lysyl oxidases; TGF, transforming growth factor; NF-κB, nuclear factor kappa B; ESC, endometrial stromal cell; ...

The activation of TGF-β receptors results in cascades of intracellular signaling ... Similarly, eATP and TGF-β also downregulated numerous genes, primarily epithelial genes (Figure S1A, B). All these ...

Cell surface receptors are central to the cell's ability to generate coordinated responses to the multitude of biochemical and physical cues in the microenvironment. However, the mechanisms by which ...