The "TGFb inhibitors – Pipeline Insight, 2021" drug pipelines has been added to ResearchAndMarkets.com’s offering. The companies and academics are working to assess challenges and seek ...

New study results suggest that integrin inhibitors have the potential to both prevent infection with SARS-CoV-2, including the Delta and Omicron variants, and to decrease TGF-β levels, resulting ...

Transforming growth factor (TGF)-β signaling is an attractive therapeutic target as it is deregulated in many cancers. But challenges remain around developing inhibitors that can specifically block ...

PERTH, Australia and TAIPEI and SHANGHAI, Oct. 20, 2021 /PRNewswire/ -- GenFleet Therapeutics, a clinical-stage biotechnology company focusing on ...

A mouse study suggests that using an inhibitor of transforming growth factor beta (TGF-beta) alongside primary therapy for cancer has clinical benefits, reducing metastases and radiation side effects.

This created a new opening for cancer therapy, the researchers thought. If cold tumors were treated with a TGF-Beta blocker, it would open the door for immunotherapy to drive tumor-killing lymphocytes ...

Recent scientific, clinical breakthroughs and high-profile industry deals have reignited the race to find the next blockbuster TGF-ß inhibitor for immuno-oncology applications.

By revealing that the TGF-beta pathway plays a protective role against uterine cancer, this work has significantly advanced our understanding of the disease and opened novel avenues for future ...

TGF-β Pathway: TGF-β is a cytokine that plays a critical role in regulating cellular processes such as proliferation, differentiation, and apoptosis. In the liver, ...

LA JOLLA, Calif., Dec. 5, 2024 /PRNewswire/ -- EpicentRx announced today that the U.S. Food and Drug Administration (FDA) granted Fast Track designation for the oncolytic adenovirus-delivered ...

It has been shown that TGF-b production is increased in the sera of OS patients. I have found that a small molecule inhibitor of TGF-β type 1 Receptor kinase, significantly reduced OS growth through ...