Clinical examination—encompassing both patient interview and physical inspection—has long served as one of the most essential ...

The phenomenon of cancer overdiagnosis, the diagnosis of a malignant tumour that, without detection, would never lead to adverse health effects, has been reported for several cancer types in different ...

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Chronic non-cancer pain, a disabling and distressing condition which is common in adults, has been declared a global public health concern and economic burden.1 Many people who experience this ...

1 School of Life and Health Sciences, Aston University, Birmingham, West Midlands, UK 2 School of Psychology, University of Birmingham, Edgbaston, Birmingham, West Midlands, UK Thus, interpersonal ...

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A network meta-analysis combines the evidence from existing randomised trials about the comparative efficacy of multiple treatments. It allows direct and indirect evidence about each comparison to be ...

Objectives Analgesics are among the most commonly used and accessible drugs in the world. They are generally well tolerated and effective if consumed appropriately. Yet, not all medicines available ...

Correspondence to Dr Veronika Williams, Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford OX2 6GG, UK; veronika.williams{at}phc.ox.ac.uk Given its scope and its place ...

1 Health Research Board – Collaboration in Ireland for Clinical Effectiveness Reviews (HRB-CICER), Health Information and Quality Authority (HIQA), Dublin, Ireland 2 Health Research Board Centre for ...

Clinicians are regularly faced with multiple and often conflicting guidelines. While clinicians may wish to reduce overuse in their practice, they may find doing so challenging when some guidelines ...

Correspondence to Dr Igho J Onakpoya, Nuffield Department of Primary Care Health Sciences, University of Oxford, Centre for Evidence-Based Medicine, Oxford OX2 6GG, UK; igho.onakpoya{at}phc.ox.ac.uk ...