More information: Felix Pahmeier et al, Antibodies targeting Crimean-Congo hemorrhagic fever virus GP38 limit vascular leak and viral spread, Science Translational Medicine (2025). DOI ...

Introduction Limited data exist on brain MRI enhancement in myelin-oligodendrocyte-glycoprotein (MOG) antibody-associated disease (MOGAD) and differences from ...

Experience has shown that the usual approach of making a vaccine for Zika or Dengue may cause the body to make misdirected immune responses and lead to worse disease if a person is later exposed to a ...

Antibodies created during a viral infection or in response to a vaccine help to prevent reinfection with that specific virus but can, in some cases, worsen infections by similar ones. This phenomenon, ...

Both neutralization and antibody-dependent cellular cytotoxicity (ADCC ... To determine the relative influence of ADCC and nAb responses on virus evolution, we performed an in-depth investigation of ...

Recent studies have shown that human DENV E protein-reactive antibodies cross-react with ZIKV but are poorly neutralizing and instead potently enhance ZIKV infection in vitro, through a mechanism ...

The virus-induced NTAN1 degradation is independent of polyubiquitylation but dependent on proteasome. Furthermore, the virus-induced N-end rule pathway suppression inhibits apoptosis and benefits ...

There is no evidence that any of the coronavirus vaccines in development worsen a coronavirus infection rather than confer immunity to it, but the phenomenon is something scientists are closely ...

EMC1-dependent stabilization enables SV40 to engage a cytosolic extraction complex that ejects the virus into the cytosol. Thus EMC1 acts as a molecular chaperone, bracing the destabilized SV40 in a ...