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PNAS25d
The Hippo pathway and p27Kip1 cooperate to suppress mitotic regeneration in the organ of Corti and the retina
We thank A.J. Hudspeth and Tri-Institutional Therapeutic Discovery Institute for codeveloping the TDI-011536 Lats kinase Inhibitor utilized in this study. We thank Dr. Renjie Chai and Dr. Joe Burns ...
C&EN1mon
Microvesicles Derived from Human Bronchial Epithelial Cells Regulate Macrophage Activation During Mycobacterium abscessus Infection
Department of Biochemistry and Molecular Biology, Oklahoma State University, Stillwater, Oklahoma 74078, United States Oklahoma Center for Respiratory and Infectious Diseases, Oklahoma State ...
C&EN1mon
Three-Dimensional Cultured Human Nasal Epithelial Cell Model for Testing Respiratory Toxicity and Neurotoxicity of Air Pollutants
Key Laboratory of Yangtze River Water Environment, Ministry of Education, College of Environmental Science and Engineering, Tongji University, Shanghai 200092, China ...
The EMBO Journal2mon
Local weakening of cell-extracellular matrix adhesion triggers basal epithelial tissue folding
This cover highlights the article PLK1 inhibition delays mitotic entry revealing changes to the phosphoproteome of mammalian cells early in division by M. Gobran, P. Lenart and colleagues. HeLa Kyoto ...
Frontiers3y
A FACS-Free Purification Method to Study Estrogen Signaling, Organoid Formation, and Metabolic Reprogramming in Mammary Epithelial Cells
Few in vitro models are used to study mammary epithelial cells (MECs), and most of these do not express the estrogen receptor α (ERα). Primary MECs can be used to overcome this issue, but methods to ...
Frontiers9y
Implications of the hybrid epithelial/mesenchymal phenotype in metastasis
Transitions between epithelial and mesenchymal phenotypes – the epithelial to ­mesenchymal transition (EMT) and its reverse the mesenchymal to epithelial transition (MET) – are hallmarks of cancer ...