Amyloid-Targeting Therapies in Alzheimer Disease: Mechanisms of Action, Efficacy, and Safety Considerations EP: 9 . Real-World Implications of Changes in CDR-SB Score in Patients Receiving Amyloid ...

High serum type I interferon (IFN) scores, measured through six chemokines, correlated with poorer lung function and health-related quality of life in patients with diffuse cutaneous systemic ...

The therapies encourage cleaning cells called microglia to attack the clumps of amyloid-beta proteins that are thought to be involved in neurodegeneration. Microglia responses to amyloid beta can lead ...

This external QC program comes free of charge to participating laboratories. The CSF biomarkers tau and amyloid ß (Aß) show promise as tools in the diagnostic work-up patients with suspected Alzheimer ...

Department of Neuroscience, Developmental, and Regenerative Biology, University of Texas at San Antonio, 1 UTSA Circle, San Antonio, Texas 78249, United States ...

Scientists at the University of Toronto studying the hermaphroditic worm Caenorhabditis elegans found that amyloid-like structures—proteins often associated with diseases like Alzheimer’s ...

Nearly one million people worldwide are plagued annually by cutaneous leishmaniasis, a devastating skin infection caused by the Leishmania parasite. Predominantly affecting vulnerable populations ...

The immunoassay measures the ratio of ptau-217 and beta amyloid 42, two distinct biomarkers of Alzheimer's, according to the Wednesday announcement. The Global CEO Initiative on Alzheimer’s Disease ...

and cerebral amyloid angiopathy independent of APOE after adjusting for age, sex, cholesterol-lowering medication use, body mass index, smoking and education at false discovery rate (FDR) p-value ...

Background Previous studies on the associations between socioeconomic status (SES) and cutaneous malignant melanoma (CMM) failed to distinguish the effects of different SES factors under an individual ...

Toxic accumulation of amyloid beta and tau proteins are two of the hallmarks of Alzheimer’s, researchers said in background notes. Amyloid beta first starts forming plaques in the brain ...

CD47 is found to play a pivotal role in this immunosuppression by inducing the production of amyloid-β (Aβ), which interacts with CD74 on B cells, leading to B-cell suppression and subsequent adaptive ...